Who is it for?

Perfect for those concerned with ageing

Why should I use it?

visible signs of ageing
dullness or uneven texture
fine lines and wrinkles
loss of firmness and elasticity – without wanting injectables or invasive treatments.

How do I use it?

Step 1: Cleanse
Start with PreCleanse to remove makeup, SPF and daily buildup. Follow with Special Cleansing Gel to gently cleanse without stripping skin.

Optional: Use Daily Microfoliant after cleansing if part of your routine.

Step 2: Renew with Phyto Nature E²
Apply Phyto Nature E² to clean skin as your first leave-on step. Allow it to absorb fully – for best results use morning and night.

Step 3: Layer serums and moisturisers
Once absorbed, layer your usual serums and moisturiser. Phyto Nature E² works seamlessly with other treatments.
Pro Tip: Follow with Phyto Nature Firming Serum and Phyto Nature Oxygen Cream for enhanced results.

Step 4: Protect (daytime only)
Finish with a broad-spectrum SPF, such as Dynamic Skin Recovery SPF50. Apply generously as the final step in your routine.

What’s in it?

Inside the formula

Regenerative Exosome Blend
Plant-derived, vegan exosomes help support regeneration across multiple layers of skin’s surface – visibly reducing the appearance of fine lines and wrinkles.

Pumpkin Enzyme
Gently exfoliates by breaking down the bonds between dead skin cells, revealing brighter, smoother-looking skin daily.

Botanical Renewal Complex
With Phyto Glycogen and Prickly Pear to help boost skin’s natural exfoliation and smoothness.

Bio-Fermented Acetyl Glucosamine
Helps hydrate skin and provide antioxidant protection.

Key Ingredients:

Pumpkin enzyme: Exfoliates to reveal brighter, smoother skin daily
Regenerative exosome blend: Acts in multiple layers of skin’s surface, visibly diminishing fine lines and wrinkles
Botanical blend with phyto glycogen + prickly pear: Visibly brightens and smooths
Bio-fermented acetyl glucosamine: Hydrates and provides antioxidant protection

Water/Aqua/Eau, Lactobacillus/Pumpkin Ferment Extract, Propanediol, Lactococcus Ferment Lysate, Ethoxydiglycol, Hydrolyzed Soy Protein, Acetyl Glucosamine, Hydroxyacetophenone, Lactic Acid, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Citrus Limon (Lemon) Peel Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Salvia Sclarea (Clary) Oil, Pyrus Malus (Apple) Fruit Extract, Viola Odorata Leaf Extract, Acacia Senegal Gum Extract, Curcuma Longa (Turmeric) Root Extract, Mucor Miehei Extract, Lavandula Spica (Lavender) Flower/Leaf/Stem Extract, Rosmarinus Officinalis (Rosemary) Leaf Oil, Litsea Cubeba Fruit Oil, Camellia Japonica Flower Extract, Glycerin, Mentha Piperita (Peppermint) Oil, Butylene Glycol, Lactobacillus Ferment, Glycogen, Urea, Caprylyl Glycol, Phospholipids, Glucosamine HCl, Xanthan Gum, PEG-40 Hydrogenated Castor Oil, 1,2-Hexanediol, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Citric Acid, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Sodium Chloride, Sodium Citrate, Disodium EDTA, Sodium Benzoate, Potassium Sorbate, Limonene, Linalool, Citral.

We are dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are complete, up-to-date and/or error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.

Brand

Dermalogica

Size

40 mL

Dermalogica Phyto-Nature e² Regenerating Daily Exosome Leave-on Treatment

Daily exosome leave-on visibly smooths and supports skin regeneration.

Formulated with next-gen exosomes and enzymes, this lightweight, silky leave-on helps reawaken skin’s natural surface renewal process, improving natural regeneration by 86%.*

Exfoliating enzymes help clear away dull surface cells, revealing smoother, brighter skin. A regenerative exosome blend acts in multiple layers of skin’s surface, visibly diminishing fine lines and wrinkles. In an independent clinical study, fine lines and wrinkles were visibly diminished in 2 weeks.**

Clinically proven results – Independent trials

visibly reduces signs of skin ageing in 2 weeks*
skin looks smoother, brighter and more refined
texture feels improved with continued use

*Independent clinical study. Results at 2 weeks, based on a reduction in visible signs of skin aging with 32 subjects, 2 applications/day. with 32 subjects, twice-daily use.

**Versus untreated skin. Based on in vitro testing.

£111.00

Inside the formula

Key Ingredients:

Reviews

Dermalogica Phyto-Nature e² Regenerating Daily Exosome Leave-on Treatment

*Independent clinical study. Results at 2 weeks, based on a reduction in visible signs of skin aging with 32 subjects, 2 applications/day. with 32 subjects, twice-daily use.

**Versus untreated skin. Based on in vitro testing.

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Dermalogica Special Cleansing Gel

Dermalogica Retinol Clearing Oil